HAZMAT PROTECT 2024, National Institute for NBC Protection, Milín, Czech Republic, September 25 -26, 2024
ERRS, 10-13th September 2024 | University of Aveiro, Aveiro | Portugal
2024
Martin Falk, Micheal Hausmann, Olga Kopečná, Myriam Schäfer, Tomáš Vičar, Jiří Toufar, Georg Hildenbrand, Lucie Dobešová, Jonas Weidner, Iva Falkova, Ondřej Polák, Alena Bačíková. Importance of Radiation Induced Foci (IRIF) in Radiation Research and Health Science. COPCA-MultIChem 2024—The 2024 Collisions Physics and Chemistry and their Applications Conference and A Workshop of the COST Action 20129: Multiscale Irradiation and Chemistry Driven Processes and Related Technologies. 15th – 18th October 2024. Aula Magna, University of Malta, Valletta, Malta. (INVITED LECTURE)
Jiří Toufar, Myriam Schäfer, Lucie Dobešová, Georg Hildenbrand, Olga Kopečná, Tomáš Vičar, Jonas Weidner, Iva Falkova, Alena Bačíková, and Micheal Hausmann and Martin Falk. Local and global post-irradiation changes in chromatin architecture at DSB sites and in the entire nucleus and their significance for DSB repair and genome stability. The Eight International Conference „Dynamics of Systems on the Nanoscale“ and the Third Conference of the COST Action „Multiscale Irradiation and Chemistry Driven Processes and Related Technologies“ DySoN-MultIChem 2024. April 08-12, 2024. Tbilisi, Georgia. (INVITED LECTURE)
Martin Falk, Micheal Hausmann, Olga Kopečná, Myriam Schäfer, Tomáš Vičar, Jiří Toufar, Georg Hildenbrand, Lucie Dobešová, Jonas Weidner, Iva Falkova, Ondřej Polák, Alena Bačíková. Implications of local and global changes in chromatin architecture after irradiation at NHEJ- or HR-DSB sites and throughout the nucleus for DSB repair and genome stability. 48th European Radiation Research Society (ERRS) Annual Meeting, September 10 – 13, 2024. Aveiro University, Aveiro, Portugal. (SELECTED FOR ORAL PRESENTATION)
Martin Falk, Micheal Hausmann, Jiří Toufar, Lucie Dobešová, Myriam Schäfer, Tomáš Vičar, Georg Hildenbrand, Jonas Weidner, Iva Falkova, Ondřej Polák, Alena Bačíková. DNA damage by different types of ionizing radiation and DNA double-strand break repair within the local chromatin environment and the overall chromatin network. MGH (Bio)Physics Seminar. October 29, 2024. Harvard Medical University, Online. (INVITED 60 min LECTURE)
Martin Falk, Tomáš Vičar, Iva Falková, Jiří Toufar, Lucie Toufarová. CURRENT OPTIONS FOR THE DETECTION OF DNA DOUBLE-STRAND BREAKS (DSB) INDUCED BY IONIZING RADIATION AND CHEMICAL AGENTS. HAZMAT PROTECT 2024: 5th Scientific Conference on CBRN Protection. September 25 – 26, 2024. National Institute for Nuclear, Biological and Chemical Protection (SUJCHBO), Milín, Czech Repaublic.
Martin Falk, Jiří Toufar, Lucie Dobešová, Olga Kopečná, Tomáš Vičar, Iva Falková, Michael Hausmann, Alena Bačíková. PERSISTING CONTRADICTORIES WITH METAL NANOPARTICLE-MEDIATED CELL RADIOSENSITIZATION. NIS COLLOQUIUM nBIO-MED: Prospects and challenges of nanomaterial application in the BIO-MEDical field. 19th April, 2024. Aula Castagnoli – Dip. Di Fisica, Universita di Torino, Torino, Italy. (INVITED 35 min LECTURE)
Hausmann M, Schäfer M, Gier T, Schmidt-Kaler F, Hudetz D, Kopečná O, Dobešová L, Huščavová E, Pagáčová E, Wolinsky M, Falkova I, Hildenbrand G, Falk M (2024) Changes of chromatin nano-organization induced by nano-particle enhanced radiation: What makes up the difference? Int. Caparica Symp Nanoparticles and Nanomaterials, 6th ISN2A 2024, 22. – 25. 01. 2024, Lissabon, Portugal.
Hausmann M, Weidner J, Schäfer M, Agosta D, Leuther J, Saleem A, Hildenbrand G, Scherthan H, Falk M (2024) Topological and geometric approaches to quantify chromatin radiation damage response on the nano-scale Int. Caparica Symp Nanoparticles and Nanomaterials, 6th ISN2A 2024, 22. – 25. 01. 2024, Lissabon, Portugal.
2023
Martin Falk, Lucie Dobešová, Ema Huščavová, Olga Kopečná, Tomáš Vičar, Jiří Toufar, Iva Falková, Michael Hausmann, Alena Bačíková, Götz Pilarczyk. IS THERE A SIMPLE EXPLANATION FOR METAL NANOPARTICLE-MEDIATED CELL RADIOSENSITIZATION? COST MultIChem 2023 “ Multiscale Irradiation and ChemistryDriven Processes and Related Technologies“. April 26-28, 2023. Vila Lanna Prague, Czech Republic. (INVITED LECTURE)
Martin Falk, Jiří Toufar, Michael Hausmann, Charlotte Nietzel, Olga Kopečná, Tomáš Vičar, Hannes Hahn, Lucie Dobešová, Iva Falková, Götz Pilarczyk, Theresa Gier, Alena Bačková. Update on the relationship between the architecture of repair foci (IRIF) and DSB repair. International Conference „Dynamics of Systems on the Nanoscale“, DySoN 2023. April 24-26, 2023. Vila Lanna, Prague, Czech Republic.
Michael Hausmann, Jonas Weidner, Myriam Schäfer, Jakob Leuther, Götz Pilarczyk, Arslan Saleem, Georg Hildenbrand, Harry Scherthan, and Martin Falk. Topological changes of the whole chromatin of cell nuclei during DNA repair as a collective response to radiation induced damages. DeGBS Meeting, September 18-20, 2023, Hohenwart Forum, Pforzheim, Germany. (INVITED LECTURE)
Martin Falk. DNA repair in the context of chromatin – an opportunity and challenge for modelling. COST Action CA20129 MultiChem Workshop “Multiscale modeling of radiation-induced biodamage for radiotherapy applications”, Particle Therapy Research Center (PARTREC), September 21-22, 2023, University Medical Center Groningen Groningen, the Netherlands. (INVITED LECTURE)
Michael Hausmann, Jonas Weidner, Myriam Schäfer, Götz Pilarczyk, Georg Hildenbrand, Harry Scherthan, Martin Falk. Radiation damage response of the whole chromatin in cell nuclei during DNA repair: An approach by topological analyses. 17th International Congress for Radiation Research (ICRR), August 27-30, 2023, Montreal, Canada.
Martin Falk, Olga Kopečná, Eva Pagáčová, Lucie Dobešová, Ema Huščavová, Jiří Toufar, Tomáš Vičar, Iva Falková, Michael Hausmann, Alena Bačíková, Götz Pilarczyk. Gold nanoparticle radiosensitizers—weak but complex effects on chromatin and whole cells after exposure to keV and MeV photon radiation. 17th International Congress for Radiation Research (ICRR), August 27-30, 2023, Montreal, Canada.
Martin Falk. Mechanism of radiosensitization through metal nanoparticles – nuclear, cytoplasmic, and/or systemic effects. MultIChem COST Action, Nanoparticle Enhanced Radiotherapy workshop. 23rd January 2023. University College London (UCL), online. (INVITED LECTURE) Michael Hausmann et al. Changes of chromatin nano-organization induced by nano-particle enhanced radiation: What makes up the difference? MultIChem COST Action, Nanoparticle Enhanced Radiotherapy workshop. 23rd January 2023. University College London (UCL), online. (INVITED LECTURE)
2022
Falkova I, Falk M, Kopecna O, Pagacova E, Golan M, Bacikova A, Kratochvilova I, Hausmann M. Freezing and thawing cells to radio-sensitize tumour cells. 47th Annual Meeting of the European Radiation Research Society (ERRS 2022), Catania, Sicily (Italy), September 21–24, 2022.
Falk M, Dobesova L, Kopecna O, Pagacova E, Gier T, Vicar T, Falkova I, Bestvater F, Toufar J, Hausmann M, Bacikova A, Kopel P, Hildenbrand G, Fedr R. New insights into metal nanoparticle-mediated effects on chromatin organization at the micro- and nano-scale: Relevance for tumor cell radiosensitization. 47th Annual Meeting of the European Radiation Research Society (ERRS 2022), Catania, Sicily (Italy), September 21–24, 2022.
Falk M, Vičar T, Gumulec J, Falková I, Kopečná O, Pagáčová E, Kolář R, Toufar J, Parsimehr E, Dobešová L, Huščavová E. New software based on artificial neural networks and deep machine learning for automatic quantification of DNA radiation damage and triage of irradiated population. Future Forces Forum (NATO), Medical Conference. 17-21st October, 2022, Prague, Czech Republic.
Falk M et al. New software using artificial neural networks for automatic quantification of radiation damage to DNA and triage of irradiated. 4th annual expert conference on protection against CBRN substances, HAZMAT PROTECT 2022, „New research challenges in the light of real CBRN events“ (https://hazmat-protect.sujchbo.cz/). State Institute of Nuclear, Chemical and Biological Protection, v. v. i., Milín, Czech Republic. 14-15 September 2022.
Falk M, Falkova I. Effects of different types of ionizing radiation on DNA from the perspective of medicine and planned manned interplanetary flights. Conference of the Society for Radiobiology and Crisis Planning of CLS JEP, CZECH MEDICAL CHAMBER, Dept. EDUCATION, „Current radiobiological findings with regard to the increased threat to the population from ionizing radiation“. 26 April 2022. Prague, Czech Republic. (INVITED LECTURE)
Falk M, Hausmann M, Falková I, Kopečná O, Pagáčová E, Bačíková A. Repair focus micro- and nano architecture in double strand break repair efficiency and pathway selection. The Mendel Genetics Conference, Brno, Czech Republic, 20-23 July, 2022.
Falk M., Hausmann M, Falková I, Kopečná O, Pagáčová E, Bačíková A. Repair focus micro- and nano architecture in double strand break repair efficiency and pathway selection. The Mendel Gentetics Conference, Brno, Czech Republic, 20-23 July, 2022.
Hausmann, M, Weidner J, Schäfer M, Kopečná O, Pagáčová E, Neitzel C, Winter R, Hahn H, Fischer E.F, Küntzelmann K, Rozo Prado, L, Falkova I, Falk M, Pilarczyk G.The impact of chromatin architecture, its geometry and topology, on radiation induced damaging and following DNA repair processes. 47th Annual Meeting of the European Radiation Research Society (ERRS 2022), Catania, Sicily (Italy), September 21–24, 2022.
Falk M. DNA damage and repair after exposure to different types of ionizing radiation – the context of carcinogenesis and antitumor radiotherapy (Poškození a reparace DNA různými druhy ionizujícího záření v kontextu karcinogeneze a protinádorové radioterapie). 13th WORLD INTERDISCIPLINARY ONCOLOGY COLLOQUIUM (PragueONCO), Jan 26–28, 2022. Prague, Czech Republic. (INVITED LECTURE)
Hausmann M, Falk M, Scherthan H, Erenpreisa J, Heermann DW, Hildenbrand G, Pilarczyk G. Irradiation and biochemistry driven (re)organization of membrane receptors and cell nucleus chromatin domains. 1st International Conference „Multiscale Irradiation and Chemistry Driven Processes and Related Technologies“ (MultIChem 2022). https://mbnresearch.com/ca20129-multichem/main. May 16-18, 2022, Boppard am Rhein, Germany. (INVITED LECTURE)
Falk M, Michael Hausmann, Wisam Mohammed Hikmat, Georg Hikldenbrand, Ivan Dellino, Mario Faretta, Iva Falková, Olga Kopečná, Eva Pagáčová, Emilie Lukasova, Alena Bačíková, Pier Giuseppe Pellicci, Götz Pilarczyk, Ema Huščavová, Myriam Schäfer, Ruth Winter, Karel Štěpka, Kyra Michalová, Zuzana Zemanová, Elham Parsimehr, Jiří Toufar, Lucie Dobešová. How nanoscale chromatin architecture and chromatin topology within the cell nucleus participates in cancer development – an example of pathogenesis of three different leukemia types. International Symposium: „Spatial-temporal genome regulation in stress- response and cell-fate change“ Lecture Hall and Virtual, BIOMEDICAL RESEARCH AND STUDY CENTRE (BMC), July 25th, 2022, RIGA, Latvia. (INVITED LECTURE) Hausmann M, Weidner J, Schäfer M, Winter R, Hahn H, Neitzel Ch, Küntzelmann K, Falkova I, Scherthan H, Falk M, Hikldenbrand G, Pilarczyk G. From Schrödinger ́s cat to his chromosomal aperiodic crystal and what an irradiated cell nucleus “thinks” about it. Symposium „Spatial-temporal genome regulation in stress- response and cell-fate change „, July 25th, 2022, Riga, Latvia. (INVITED LECTURE)
2021
Martin Falk, Iva Falk and Leos Navratil. Conference Opening. Experiences with dealing with the consequences of the tornado that hit the South Moravian Region on 24 June 2021 from the perspective of representatives of the IZS and KÚ – Seminar of the Society for Radiobiology and Crisis Planning of the Czech Medical Society Jan Evangelista Purkyně (SRCP CzMA). November 5, 2021. Lecture Hall of the Medical House, Prague, Czech Republic.
Martin Falk, Michael Hausmann, Olga Kopečná, Eva Pagáčová, Charlotte Neitzel, Iva Falková, Tatiana Chramko, Lucie Dobešová, Jiří Toufar, Elham Parsimehr. Biological effects of ionizing radiation of different types as manifested by DNA damage and repair at the micro-scale and nano-scale. Brno Oncology Days (BOD). October 13-15, 2021. Brno, Czech Republic. (INVITED LECTURE)
Michael Hausmann, Charlotte Neitzel, Hannes Hahn, Ruth Winter, Iva Falkova, Dieter W. Heermann, Götz Pilarczyk, Georg Hildenbrand, Harry Scherthan, Martin Falk. Space and time in the universe of the cell nucleus after ionizing radiation attacks: a comparison of cancer and non-cancer cell response. The 1st International Electronic Conference on Cancers: Exploiting Cancer Vulnerability by Targeting the DNA Damage Response, Part of INTERNATIONAL ELECTRONIC CONFERENCE ON CANCERS (IECC). 1–14 Feb 2021, ONLINE. (Published in Cancers special issue proceedings, INVITED LECTURE)
Michael Hausmann1, Götz Pilarczyk, Georg Hildenbrand, Martin Falk, Dieter W. Heermann, Harry Scherthan. Ionizing radiation attacks on chromatin of the cell nucleus: Impact of chromatin nano-architecture on the formation of damage sites and repair complexes. ConRad, 2021: – Global Conference on Radiation Topics – Preparedness, Response, Protection and Research. May 10 to 12, 2021. Munich, Germany.
Jiri Toufar, Lucie Dobesova, Eva Pagacova, Olga Kopecna, Iva Falkova, Alena Bacikova, Michael Hausmann & Martin Falk. Proteins of double-strand break and western blot analysis. XLII. Days of Radiation Protection (DRO). November 8-12, 2021. ONLINE
Elham Parsimehr, Lucie Dobesova, Jiri Toufar , Eva Pagacova, Olga Kopecna, Iva Falkova, Alena Bacikova, Michael Hausmann & Martin Falk. The relationship between PD-L1/PD-1/MHC-1/Her2/and other immune or oncogenic receptors. XLII. Days of Radiation Protection (DRO). November 8-12, 2021. ONLINE
Lucie Dobesova, Jiri Toufar , Eva Pagacova, Olga Kopecna, Iva Falkova, Alena Bacikova, Michael Hausmann & Martin Falk. Radiosensitizers in radiotherapy – Gold Nanoparticles. XLII. Days of Radiation Protection (DRO). November 8-12, 2021. ONLINE
Martin Falk: Elham Parsimehr, Charlotte Neitzel, Lucie Dobešová, Jiří Toufar, Elizaveta Bobkova, Theresa Gier, Georg Hildenbrand, Abin Biswas, Lucie Jezkova, Olga Kopečná, Eva Pagáčová, Iva Falkova, Tatyana Chramko, Elena Smirnova, Mariia Zadneprianetc, Dieter W. Heermann, Andreas Hofmann, David Nagel, Felix Bestvater, Götz Pilarczyk, Alena Bačíková, Elena Kulikova, Tatiana Bulanova, Alla Boreyko, Marie Davidkova, Anna Michaelides, Martin Falk, Michael Hausmann, and Evgeny Krasavin. Superresolution microscopy in research of IRIF nanoarchitecture and biological effects of high-LET ions. „NUCLEAR PHYSICS METHODS IN LIFE SCIENCES: NEURORADIOBIOLOGICAL RESEARCH AND NEW APPROACHES TO RADIATION THERAPY OF TUMORS“. April 27-28, 2021. Joint Institute for Nuclear Research (JINR), Dubna, Russia. (INVITED LECTURE)
Tomáš Vičar, Martin Falk (corresp. au.), Iva Falková, Jaromír Gumulec, Radim Kolář, Olga Kopečná, Eva Pagáčová. Automatic Analysis of Ionizing Radiation-Induced Foci (IRIFs) and Extraction of Advanced IRIF Parameters with our Newly-Developed Software Based on Artificial Neural Networks and Deep Learning. 46th European Radiation Research Society Meeting (ERRS2021). November 26-30, Caen, France. (POSTER AWARD)
Jiri Toufar, Elham Persimehr, Lucie Dobesova, Elizaveta Bobkova, Hannes Hahn, Charlotte Neitzel, Ruth Winter, Götz Pilarczyk, Georg Hildenbrand, Olga Kopecna, Eva Pagacova, Iva Falkova, Alena Bacikova, Tatiana Bulanova-Chramko, Mariia Zadneprianetc, Elena Kulikova, Alla Boreyko, Evgeny Krasavin, Dieter W. Heermann, Harry Scherthan and Martin Falk (corresp. au.) and Michael Hausmann. Functional Micro- and Nano-Scale Architecture of DNA Double Strand Break Repair Foci (IRIFs) in Normal and Cancer Cells – Implications for DSB Repair and Cell Radiosensitivity. 46th European Radiation Research Society Meeting (ERRS2021). November 26-30, Caen, France. (LECTURE)
Martin Falk. DeGBS General Meeting: Laudatio on Prof. Dr. Rer. Nat. Michael Hausmann, Ph.D. on the occasion of the prestigious Ulrich-Hagen Prize. Online. (INVITED LECTURE)
Martin Falk, Michael Hausmann, Evgeny Krasavin, Olga Kopecna, Eva Pagacova, Elizaveta Bobkova, Iva Falkova, Hannes Hahn, Charlotte Neitzel, Lucie Dobesova, Tatiana Bulanova-Chramko, Mariia Zadneprianetc, Georg Hildenbrand, Jiri Toufar, Elham Persimehr, Alena Bacikova, Ruth Winter, Götz Pilarczyk, Elena Kulikova, Alla Boreyko. DNA damage and repair research in the era of super-resolution microscopy and planed interplanetary space missions. University of Naples Federico II, Dec 2021, Naples, Italy. (INVITED LECTURE)
Martin Falk, Michael Hausmann, Lucie Dobešová, Theresa Gier, Olga Kopečná, Eva Pagáčová, Tomáš Vičar, Felix Bestvater, Jiří Toufar, Franz Schmidt‐Kaler, Alena Bačíková, Pavel Kopel, Radek Fedr, Georg Hildenbrand, Frederik Wenz, Elham Parsimehr. Challenges and Contradictions in Metal Nanoparticle‐Mediated Radiosensitization. ADVANCED STRATEGIES FOR RADIOTHERAPY—From the Lab Bench to Medical Applications. Interdisciplinary Center for Nanotechnologies & Radiation-Based Cancer Therapies. November 15-17, 2021. University of Paris-Saclay, Paris, France. (INVITED LECTURE)
2020
Martin Falk. Interplay between chromatin architecture and radiation properties – consequences for DNA damage and repair. Epigenetics in the era of coronavirus. Biofyzikální ústav , Akademie věd České republiky, v. v. i., Centrum Epigenetiky, September 3, 2020. Freskový sál na Zelném trhu, Brno, Czech Republic.
Martin Falk, Evgeny Krasavin, Michael Hausmann, Lucie Ježková, Tatiana Chramko, Olga Kopečná, Eva Pagáčová, Alla Boreyko, Albin Biswas, Theresa Gier, Charlotte Neitzel, Iva Falková, Mariia Zadneprianetc, Elena Kulikova, Elena Smirnova, Georg Hildenbrand, Alena Bačíková, Tomáš Perečko, Jana Perečková, Lucie Dobešová, Vladimír Rak, Dieter W. Heermann, Andreas Hofmann.Biological effects of ionizing radiation of different types as manifested by DNA damage and repair at the micro-scale and nano-scale. „Days of the Czech Republic at the United Institute for Nuclear Research (JINR), Dubna”. March 29 – April 1, 2020. Dubna, Russia, ONLINE. (INVITED LECTURE)
Martin Falk. DNA damage and repair in normal and tumour cells – the micro-scale and nano-scale views. The Sixth International Conference „Dynamics of Systems on the Nanoscale“, DySoN 2020. November 23-27, 2020. Regina Elena Hotel, Santa Margherita Ligure, Italy. (INVITED LECTURE)
2019
Falk M. et al. Critical damage in frozen and thawed cells. Symposium on Cell Biology and Pathology, 28-29th May 2019, Brno, Czech Republic
Gumulec J. et al. Image analysis of microscopic image data using machine learning approaches. Symposium on Cell Biology and Pathology, 28-29th May 2019, Brno, Czech Republic
Perečko T. et al. Neutrophils: Friends or Foes. Symposium on Cell Biology and Pathology, 28-29th May 2019, Brno, Czech Republic
Lee J-H. et al., Single Molecule Localization Microscopy of Nanoprobes to Study Chromatin Architecture, Function and Dynamics. Symposium on Cell Biology and Pathology, 28-29th May 2019, Brno, Czech Republic
Dobešová L. et al. Radiosensitizing effect of metal nanoparticles. Symposium on Cell Biology and Pathology, 28-29th May 2019, Brno, Czech Republic
Falk M., Ježková L, Hausmann M, Lee Jin-Ho, Kopečná O, Pagáčová E, Falková I, Bobkova E, Bačíková A, Krasavin E, Kozubek S. Micro-scale and nano-scale complexity of DNA double-strand break repair foci induced by accelerated ions of similar LET. XLI DRO (Radiation Protection Days). November 4-8, 2019. Mikulov castle, Mikulov, Czech Republic.
Hausmann M et al. Localization microscopy towards understanding of the impact of nanotopology of repair clusters after DNA radiation damaging. XLI DRO (Radiation Protection Days). November 4-8, 2019. Mikulov castle, Mikulov, Czech Republic.
Kopečná O., Falk M., Masařík M., Horáková Z., Falková I., Pagáčová E., Bačíková A., Depeš D., Svobodová M., Gumulec J., Raudenská M., Binková H., Kozubek S. Possibilities of γH2AX/53BP1 foci quantification as a potential predictive marker of head and neck tumor radiosensitivity: analysis of the 30 patient cohort. XLI DRO (Radiation Protection Days). November 4-8, 2019. Mikulov castle, Mikulov, Czech Republic.
Falková I., Kopečná O., Pagáčová E., Bačíková A., Golan M., Kratochvílová I. and Falk M. Freezing and thawing cells to radio-sensitize tumors? XLI DRO (Radiation Protection Days). November 4-8, 2019. Mikulov castle, Mikulov, Czech Republic.
Pagáčová E., Kopečná O., Falková I., Bačíková A., Falk M. Analysis of metal nanoparticle radiotoxicity. XLI DRO (Radiation Protection Days). November 4-8, 2019. Mikulov castle, Mikulov, Czech Republic.
Hausmann M., Lee J.-H., Maus E., Brieger E., Muhtadi R., Wagner E., Bobkova E., Bestvater F., Schumann S., Falkova I., Falk M., Pilarczyk G., Hildenbrand G., Scherthan H. A Pointillist View on Particle Tracks and DNA-Repair in 3D-Conserved Cell Nuclei by means of Super-Resolution Localization Microscopy. 1st Biophysics Collaboration Meeting, 20-22 May 2019, GSI Darmstadt, Germany. (INVITED LECTURE)
Hausmann M., Lee J.-H., Maus E., Hofmann A, Pilarczyk G., Heermann D.W., Falkova I., Falk M., Hildenbrand G., Scherthan H. Analysis of the nano-topology of repair clusters by localization microscopy: Towards understanding of topological impact on repair pathway decision. 16th International Congress of Radiation Research (ICRR 2019), 25th-29th August 2019, Manchester, England. (selected for oral presentation)
Falkova I., Pagáčová E., Kopečná O., Gumulec J., Raudenská M., Vičar T., Bačíková A., Horáková Z., Binková H., Kozubek S., Masařík M., Falk M. (corresp. au.). Inter-individual and cell type-specific differences in response to radiation-induced DNA damage of different cell types isolated from patients’ head-and-neck tumors. 16th International Congress of Radiation Research (ICRR 2019), 25th-29th August 2019, Manchester, England. (poster presentation)
Falk M., Ježková L., Hausmann M., Lee J.-H., Kopečná O., Pagáčová E., Falková I., Bobkova E., Bačíková A., Smirnova E., Zadneprianetc M., Kulikova E., Bulanova T., Boreyko A., Krasavin E., Davidkova M., Kozubek S. Micro-scale and nano-scale complexity of DNA double-strand break repair foci induced by accelerated ions of similar LET. 16th International Congress of Radiation Research (ICRR 2019), 25th-29th August 2019, Manchester, England. (selected for oral presentation)
Falková I et al. Relevance of DNA double strand break repair in head and neck tumor cell radioresistance. Chromatin Architecture in Cancerogenesis and (Particle Enhanced) Radiation Treatment (discussion workshop on novel approaches). September 21, 2019. International Academic Forum Heidelberg (IWH), KIP, Heidelberg University, Heidelberg, Germany. (INVITED LECTURE)
Pagáčová E et al. (Falk M. presenting and corresponding author). The promises and contradictions of nanoparticle-mediated tumor cell radiosensitization. Chromatin Architecture in Carcinogenesis and (Particle Enhanced) Radiation Treatment. September 21, 2019. International Academic Forum Heidelberg (IWH), KIP, Heidelberg University, Heidelberg, Germany. (INVITED LECTURE)
Falk M. Current possibilities to monitor DNA damage and repair. Meeting on Biodosimetry. National Radiation Protection Institute (SURO), 23rd May 2019, Prague, Czech Republic.
2018
Falk M. Spatio-temporal aspects of DNA damage and repair upon action of ionizing radiations of different types (60 min Educational Lecture). World Congress on Medical Physics & Biomedical Engineering. June 3-8, 2018. Prague, Czech Republic. (INVITED LECTURE)
DNA damage and repair in normal and tumor cells upon cell exposure to ionizing radiation of different quality. BIT’s 8th Annual World Congress of Molecular & Cell Biology-2018, October 16-18, 2018. Fukuoka, Japan. (INVITED LECTURE)
Falková I. et al. Are Myelodysplastic Syndromes (MDS) a Chromatin Structure Disease. BIT’s 8th Annual World Congress of Molecular & Cell Biology-2018, October 16-18, 2018, Fukuoka, Japan.
Falk M. Multiple mechanisms of metal nanoparticle-mediated radiosensitization of tumor cells? NANOSCIENCE MEET 2018: Annual conference on Nanoscience, Nanotechnology and Advanced materials. November 26-28, 2018. Bali, Indonesia. (INVITED LECTURE)
Bačíková A. et al. Single Molecule Localization Microscopy as a promissing tool for gH2AX/53BP1 foci exploration. XL. Dny radiační ochrany (DRO2018), 5. – 9. 11. 2018, Zámek Mikulov, Czech Republic.
Pagáčová E. Tumor Cell Radiosensitivity and Nanoparticles. XL. Dny radiační ochrany (DRO2018), 5. – 9. 11. 2018, Zámek Mikulov, Czech Republic.
Lee J.-H. et al. Mechanisms and Challenges for Understanding Radiation Induced Changes in Chromatin Nanoarchitecture. XL. Dny radiační ochrany (DRO2018), 5. – 9. 11. 2018, Zámek Mikulov, Mikulov, Czech Republic.
Horáková Z. DNA damage and its mechanism in cell cultures of head and neck tumor cells upon experimental irradiation. XL. Dny radiační ochrany (DRO2018), 5. – 9. 11. 2018, Zámek Mikulov, Mikulov, Czech Republic.
Kopečná O. et al. Applicability of gH2AX/53BP1 foci detection as potential predictive markers of head and neck tumor radioresistance. XL. Dny radiační ochrany (DRO2018), 5. – 9. 11. 2018, Zámek Mikulov, Mikulov, Czech Republic.
Falk M., Dellino I., Faretta M., Hausmann M., Falková I., Kopečná O., Pagáčová E., Bobková E., Bačíková A., Lukášová E., Kozubek S., Pelicci PG. Higher-order chromatin structure in pathogenesis of the acute promyeloctic leukemia. COST Action CA15214 Workshop: Nuclear Lamins, Nuclear Organization And Transcription. 4-5th July 2018, Riga, Latvia.
Falková I., Pagáčová E., Michalová K., Zemnová Z., Štěpka K., Matula P., Kozubek S. and Falk M. Chromosomal rearrangements in myelodysplastic syndromes. COST Action CA15214 Workshop: Nuclear Lamins, Nuclear Organization And Transcription. 4-5th July 2018, Riga, Latvia.
Falková I., et al. Study of radiosensitivity and DNA repair in different cell lines isolated from head and neck tumors. COST Action CA15214 Workshop: Nuclear Lamins, Nuclear Organization And Transcription. 4-5th July 2018, Riga, Latvia.
Martin Falk, Falková, Iva – Pagáčová, Eva – Kopečná, Olga – Bačíková, Alena – Šimek, Daniel – Golan, Martin – Klejdus, B. – Varga, K. – Teplá, O., Kratochvílová, Irena. Critical defects in cryopreserved cell nuclei: DNA structure changes. CRYO20185 (5th Annual Meeting of the Society for Cryobiology): Scientific Challenges of Cryobiology. 10-13 July, Madrid, Spain. Abstract In: Cryobiology (Elsevier) 2018, 85(12), pp. 135-135. ISSN 0011-2240.
Golan, Martin – Přibyl, J. – Pešl, M. – Jelínková, Š. – Acimovic, I. – Jaroš, J. – Rotrekl, V. – Falk, Martin – Skládal, P. – Kratochvílová, Irena. Human fibroblast post-thaw regeneration monitored by AFM and fluorescence microscopy. CRYO20185 (5th Annual Meeting of the Society for Cryobiology): Scientific Challenges of Cryobiology. 10-13 July, Madrid, Spain. Abstract In: Cryobiology (Elsevier) 2018, 85(12), pp. 133-134. ISSN 0011-2240.
Falk M., Falková I., Pagáčová E., Kopečná O., Bačíková A., Varga K., Golan M, Kratochvílová I. Complex description of cryopreserved cell nuclei defects by immunofluorescence microscopy: DNA lesions, chromatin decondensation, nuclear membrane ruptures. The Society for Low Temperature Biology (SLTB) Meeting, 6th September 2018, Prague, Czech Republic (1st Prize for poster presentation).
Pagáčová E., Falk M., Falková I., Kopečná O., Michalová K., Kozubek S. Chromosomal instability of the chromosome 5 in myelodysplastic syndrome. Genetic Conference of The Gregor Mendel Genetic Society, 12-14th September 2018, Bratislava, Slovakia.
Falková I. et al. Radio-sensitization of resistant head and neck tumor cells by metal nanoparticles. NANOSCIENCE MEET 2018: Annual conference on Nanoscience, Nanotechnology and Advanced materials. November 26-28, 2018, Bali, Indonesia. Invited lecture. Falk M et al. Radiobiology and Cancer Treatment – Current Research Topics. Interactions of Ionizing Radiation with Live Organisms – Seminar of The Society for Radiobiology and Crisis Planning of the Czech Medical Association of Jan Evangelista Purkyne (SRKP ČLS JEP) and University of Defense, 11th November 2018, Hradec Kralove, Czech Republic.
2017
Falk M et al. Tumor cell radiosensitization-ion beams and metal nanoparticles. 3rd International Conference on Systems and Synthetic Biology, July 20-21, 2017, Munich, Germany. (INVITED LECTURE)
Falková I. et al., Relationship between chromatin structure and chromosomal rearrangements in myelodysplastic syndromes. 3rd International Conference on Systems and Synthetic Biology, July 20-21, 2017, Munich, Germany.
Falk M et al. Metal nanoparticles in tumor cell radiosensitization. INTERNATIONAL CONFERENCE ON FUNCTIONAL NANOMATERIALS AND NANODEVICES, 24-27 September 2017, Budapest, Hungary. (INVITED LECTURE)
Falk M. Sensitive monitoring of DNA damage and repair in biodosimetry and cancer research. The Research Institute of Nuclear Engineering, University of Fukui, 15-23 March 2017, Tsuruga, Japan. (INVITED LECTURE)
Falkova I. et al. DNA Repair in Head & Neck Cancers and their Radiosensitivity. The Research Institute of Nuclear Engineering, University of Fukui, 15-23 March 2017, Tsuruga, Japan. (INVITED LECTURE)
Falk M. et al., Confocal Microscopy in research od DNA damage and repair: implications on cacncer, Advanced Techniques Days – New possibilities in high-speed spinning disk confocal microscopy; 9. 01. 2017, Charles University, Faculty of Science, Prague, Czech Republic. (INVITED LECTURE)
Falk M. Renaissance of Radiobiology in the New Millennium. 2-h lecture for National Radiation Protection Institute (SURO) and Nuclear Physics Inctitute of the Czech Academy of Sciences, 12th April 2017, Prague, Czech Republic. (INVITED LECTURE)
Falk M, Štefančíková L, Lacombe S, Salado D, Porcel E, Pagáčová E, Tillement O, Lux L, Depeš D, Falková I, Bačíková A, Kozubek S, Horáková Z, Falková I. 10–14 September 2017; Jerusalem, Israel; https://2017.febscongress.org
Falková I, Falk M, Pagáčová E, Štěpka K, Michalová K, Zemanová Z, Matula P. Relationship between chromatin structure and chromosomal rearrangements in myelodysplastic syndromes. 10–14 September 2017; Jerusalem, Israel; https://2017.febscongress.org
Falková I, Pagáčová E, Falk M (corresp. au.), Štěpka M, Lukášová E, Michalová K, Zemanová Z, Matula P, Kozubek S. Chromosomal rearrangements in myelodysplastic syndromes. October 2-6, 2017, Varadero, Cuba.
Ježková L, Zadneprianetc M, Kruglyakova E, Bulanova T, Smirnova E, Boreyko A, Krasavin E, Falková I, Valentová O, Davídková M, Kozubek S, Depeš D, and (corresp. au.). Particles with similar LET values generate DNA breaks of different complexity and reparability: a high-resolution microscopy analysis of γH2AX/53BP1 foci. October 2-6, 2017, Varadero, Cuba.
Kopečná O., Masařík M., Horáková Z., Falk M., Falková I., Bačíková A., Depeš D., Hoferová Z., Pagáčová E., Kozubek S. Study of radiosensitivity and DNA repair in different cell lines isolated from head and neck tumors. 6th EU-US Conference on Repair of Endogenous DNA Damage, September 24-28, 2017, University of Udine, Udine, Italy.
Falk M. et al. “Micro-scale DNA damage and double-strand break repair compared for high-LET ions of similar LET and low energy. Project Excellence Workshop, 2017, Brno, CR.
2016
Falk M. “Ionizing radiation – a double-edged sword in biology and medicine” (Ionizující záření – dvousečný meč v biologii a medicíně), 60th Student Conference (60. Studentská vědecká konference). 25th May, 2016, Masaryk University, Medical Faculty, Brno, Czech Republic. (Plenary Lecture, invited)
Falk M., Falková I., Ježková L., Bačíková A., Pagáčová E., Lukášová E., Štefančíková L., Davídková M., Boreyko A., Krasavin E., Kozubek S. Účinky různých druhů ionizujícího záření na buňku a možnosti jejich cílené modifikace. Conference on ’30 let od havárie Jaderné elektrárny v Černobylu‘, 6th May 2016, Prague, Czech Republic. (Invited lecture)
Štefančíková L., Lacombe S., Salado D., Porcel E., Pagáčová E., Tillement O., Lux F., Depeš D., Falková I., Bačíková A., Kozubek S., and Falk M (presenting author). The mechanism of metal nanoparticle-mediated radiosensitization of tumor cells may be independent of DNA damage amplification and DNA repair inhibition. 7th World Nano Conference, June 20-21, 2016, Cape Town, South Africa. (Falk M presenting author, Invited)
Falk M. Towards a complex view on DNA damage and repair – epigenetic and spatio-temporal aspects. 2nd International Conference on Systems and Synthetic Biology, August 18-20, 2016. London, UK. (Plenary Lecture, invited)
Falk M. DNA Repair in Head and Neck Cancers and their Radiosensitivity. 6th International Conference on Genomics & Pharmacogenomics September 12-14, 2016. Berlin, Germany. (INVITED LECTURE)
Falk M. Chromatin structure and chromosomal rearrangements in CD34+ cells and lymphocytes from Myelodysplastic syndromes (MDS) patients. 6th International Conference on Genomics & Pharmacogenomics September 12-14, 2016, Berlin, Germany. (Keynote lecture)
Svobodova M., Gumulec J., Raudenska M., Polanská H., Balvan J., Fojtu M., Binkova H., Horakova H., Kostrica R., Babula P., Falk M., Falková I., Kopečná O., Bačíková A., and Masarik M. Study and characterization of primary tumour cell lines of head and neck carcinoma and their malignant potential. Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic. (New & Notable, Invited)
Horáková Z., Depeš D., Masařík M., Falk M., Falková I., Kopečná O., Bačíková A., Kozubek S., Binková H., Svobodova M., Gumulec J., Raudenska M., Polanská H, Balvan J., Fojtu M., Kostrica R., Babula P., and Masarik M. A step towards personalized therapy in head & neck cancers: How different cell types isolated from H & N tumors respond to irradiation? Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic. (INVITED LECTURE)
Michaelidesová A., Vachelová J, Konířová J., Havránek V., Štursa J, Zach V., Davídková M, Falková I., Falk M. Cell response of normal human fibroblasts to irradiation by protons and alpha particles. Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic. (INVITED LECTURE)
Falk M. The biological mechanism of metal nanoparticle-mediated radiosensitization. International Conference „Dynamics of Systems on the Nanoscale“ (DySoN 2016), 3rd -7th October, Bad Ems, Germany. (INVITED LECTURE)
Falk M. Detection of DSB repair foci as a potent tool in biodosimetry and cancer research. Future Forces Forum, Medical Workshop, October 20, 2016, Prague, Czech Republic. (INVITED LECTURE)
Horáková Z., Binková H., Falk M., Masařík M., Falková I., Depeš D., Gumulec J., Bačíková A., Pagáčová E., Kostřica R. In vitro stanovení radiosenzitivity nádorů hlavy a krku. XL. Brněnské onkologické dny a XXX. konference pro nelékařské zdravotnické pracovníky, 27.–29. April, 2016, Brno, Czech Republic. Abstract in: Klinická onkologie 29/Suppl2, 2016.
Falk M., Štefančíková L., Ježková L., Lacombe S., Pagáčová E., Depeš D., Davídková M., Falková I., Bačíková A., Zadneprianetc M., Daniela Salado., Porcel E., Tillement O., Lux F., Vachelová J., Michaelides A., Boreyko A., Krasavin E., Lukášová E., Kozubek S. Response of normal and tumor cells to ionizing radiations of different qualities. Strategy 21, 8th June 2016, Brno, Czech Republic.
Štefančíková L., Lacombe S., Salado D., Porcel E., Pagáčová E., Tillement O., Lux F., Depeš D., Kozubek S., and Falk M. The mechanism of metal nanoparticle-mediated tumor cells radiosensitization – is nuclear DNA damage necessary? Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic.
Falková I., Pagáčová E., Bačíková A., Michalová K., Zemanová Z., Štěpka K., Matula Pa., and Falk M. Relationship between chromatin structure and chromosomal rearrangements in myelodysplastic syndromes. Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic.
Golan M et al. Viability of cryopreserved cells, state of their nuclei and cryoprotectants’ properties. Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic.
Michaelidesová A., Vachelová J., Konířová J., Vondráček V., Davídková M., Falková I., Falk M. When proton meets a cell. Conference on Cell Biology and Radiobiology – Satellite Symposium of the ‚6th International Conference on Genomics and Pharmacogenomics‘ held in Berlin, 9th-10th September 2016, Brno, Czech Republic.
Štefančíková L., Pagáčová E., Lacombe S., Depeš D., Salado D., Porcel E., Tillement O., Lux F., Kozubek S. and Falk M. Nanoparticles to improve tumor radiotherapy. Functional Organization of the Cell Nucleus Symposium, 3rd November 2016, Prague, Czech Republic.
Kopečná O. et al. Krok kupředu ke kombinované personalizované terapii: Jak odpovídají různé typy buněk izolované z nádorů hlavy a krku na ozáření? XXXVIII. DNY RADIAČNÍ OCHRANY, 7. – 11. 11. 2016, Zámek Mikulov, Czech Republic.
Štefančíková L., Falk M., Lacombe S., Depeš D., Porcel E., Pagáčová E., Salado D., Tillement O., Lux F., Kozubek S. Nový pohled na radiosenzitizační efekt kovových nanočástic. XXXVIII. Dny radiační ochrany (DRO), 7. – 11. 11. 2016, Zámek Mikulov, Czech Republic.
Falk M., Hofer M., Komůrková D., Falková I., Bačíková A., Klejdus B., Pagáčová E., Štefančíková L., Weiterová L., Angelis K., Kozubek S., Dušek L., Galbavý Š. XXXVIII. DNY RADIAČNÍ OCHRANY, 7. – 11. 11. 2016, Zámek Mikulov, Czech Republic.
Horáková Z., Falk M., Falková I., Kopečná O., Bačíková A., Kozubek S., Depeš D., Binková D., Gál B., Svobodová M., Gumulec J., Raudenská M., Polanská H., Masařík M. Předléčebné stanovení radiosensitivity nádorů hlavy a krku, cesta k individualizované terapii? XXXVIII. Dny radiační ochrany (DRO), 7. – 11. 11. 2016, Zámek Mikulov, Czech Republic.
Falk M., Falková I., Pagáčová E., Bačíková A., Golan M., Šimek D., Ignácová S.S., Mičová J., Šebera J., Richter J., Řeha D., Follett S.E., Elliott K.W., Varga K., Kratochvílová I. Viability of cryopreserved cells, state of their nuclei and properties of cryoprotectants. CRYO2016: The 53rd Annual Meeting of the Society for Cryobiology, July 24-27, 2016, Ottawa, Canada. Abstract In: Cryobiology (Elsevier) 2016, 73, pp. 423-423. ISSN 0011-2240 Ježková L., Borezko A., Bulanova T., Falk M., Falkova I., Davidkova M., Koyubek S., Krasavin E., Kruglzakova E., Valentova O., Smirnova E., Yadneprianetc M. Time and dose response of γH2AX and 53BP1 foci in human fibroblasts exposed to radiation of different qualities. Conference on Radiation & Health titled „Public Health Impact of Current Sources of Radiation Exposure: New Data and Insights from Biology, Epidemiology, and Statistics“, October 15-17, 2016, Waikoloa Village, Hawaii.
2015
Falk M. et al. New trends in radiotherapy from a biologist’s point of view – from photons to accelerated ions and combined radio-sensitizing therapy, current and future possibilities of tumor cell radio-sensitization. XXIV. Conference of rehabilitation and physical- and balneo-medicine, February 6 – 7, 2015, Jáchymov, Czech Rep.
Falk M. Higher-order chromatin structure in induction and repair of DNA double strand breaks upon the action of ionizing radiation of different quality. Functional Organization of the Cell Nucleus Symposium. October 19, 2015, Prague, Czech Rep. (INVITED LECTURE)
Depeš D., Falk M., Masařík M., Falková I., Gumulec J., Bačíková A., Horáková Z., Pagáčová E., Binková H. Analýza možností využití detekce gH2AX/53BP1 ohnisek a monitorování reparace dvouřetězcových zlomů DNA pro pre-terapeutické stanovení radiosensitivity nádorů hlavy a krku. XXXVII. DNY RADIAČNÍ OCHRANY. November 09 – 13, 2015, Mikulov, Czech Rep.
Depeš D., Falk M. Automatické počítání reparačních ohnisek DSB v buněčných jádrech pomocí programu FociCounter 1.0. XXXVII. DNY RADIAČNÍ OCHRANY. November 09 – 13, 2015, Mikulov, Czech Rep.
Michaelides A., Vachelová J., Pachnerová-Brabcová K., Sýkorová P., Depeš D., Falk M., Falková I., Vondráček V., Davídková M. Vliv dávkového příkonu na odezvu buněčných kultur. XXXVII. DNY RADIAČNÍ OCHRANY. November 09 – 13, 2015, Mikulov, Czech Rep.
Falk M. Induction of DNA double strand breaks (as a double-edge sword) in cancer development and treatment. Seminář „Molekulární genetika nádorových onemocnění“ pořádaný v rámci výzkumného programu QUALITAS Strategie AV21. 3. prosince 2015, Prague, Czech Republic.
Falk M (Chair). AWHP Aspects of work of helping professions (Aspekty práce pomáhajících profesí): Imigrace – bezpečnostní a zdravotní rizika. 2. 10. 2015., Prague, Czech Rep.
Pagáčová E., Falk M., Falková I., Štěpka K., Lukášová E., Michalová K., Zemanová Z., Matula P., Kozubek S. Relationship between chromatin structure and chromosomal rearrangements in myelodysplastic syndromes. International Conference on Chromosomal Genetics and Evolution (ICCGE 2015), February 16-17 2015, London, United Kingdom
Zadneprianetc M., Boreyko A., Bulanova T., Falk M., Falkova I., Davídková M., Ježková L., Kozubek S., Krasavin E., Kruglyakova E., Valentová O. IRIF cluster formation and structure in human fibroblasts after irradiation with boron ions and g-rays. RAD 2015, Second International Conference on Radiation and Dosimetry in Various Fields of Research. May 27 – 30, 2014. Niš, Serbia.
Falk M., Lukášová E., Štefančíková L., Falková I., Kozubek S. Amifostine, a redioprotective drug acting as radical scavenger, preferentially protects active genes in decondensed chromatin. ICRR 2015 – 15th International Congress of Radiation Research. May 25 – 29, 2015, Kyoto, Japan.
Falk M., Falková I., Ježková L., Davídková M., Bačíková A., Zadneprianetc M., Pagáčová E., Vachelová J., Michaelidesová A., Lukášová E., Boreyko A., Krasavin E.A., Kozubek S. DSB repair in normal and radioresistant tumor cells exposed to g-rays, protons of different energies, and high-LET ions. ICRR 2015 – 15th International Congress of Radiation Research. May 25 – 29, 2015, Kyoto, Japan.
Ježková L., Boreyko A., Bulanova T., Falk M., Falkova I., Davídková M., Kozubek S., Krasavin E., Kruglyakova E., Valenova O., Zadneprianetc. Analysis of DSB repair and structure of IRIF clusters induced by high- and low-LET radiations. ICRR 2015 – 15th International Congress of Radiation Research. May 25 – 29, 2015, Kyoto, Japan.
Štefančíková L., Salado D., Porcel E., Maury P., Pagáčová E., Bolsa M., Ivošev V., Sanchez G.J., Roux S., Tillement O., Lux F., Falk M. and Lacombe S. Metal- and lanthanide-based nanoparticles improve the performances of radiotherapies. Nanoparticles. Advances in nanopraticulate carriers: Applications in diseases and infections. October 19th-21st, 2015, Institut Pasteur, Paris, France.
2014
Falk M. Indukce chromosomálních aberací ionizujícím zářením různých kvalit. XXIII. konference rehabilitační, fyzikální a balneo medicíny, 7. – 8.2.2014, Jáchymov, Czech Republic. (INVITED LECTURE)
Falk M. Epigenetics and higher-order chromatin structure in regulation of fundamental nuclear processes including DNA repair (Invited Lectute). International Workshop on Nuclear Architecture. Istitutio Superiore di Sanitá (Italian NIH, Prof. Alessandro Giuliani), April 22 – 28, 2014, Roma, Italy. (INVITED LECTURE)
Lukášová E., Kořistek Z., Klabusay M., Ondřej V., Grigoryev S., Bačíková A., Řezáčová M., Vávrová J., Kohútová V., (presented by) Falk M., Kozubek S. DNA damage and repair in the context of chromatin structure and function – the influence of cell differentiation and quality of ionizing radiation. 13th International Workshop on Radiation Damage to DNA, June 14-18, 2014, Massachusetts Institute of Technology (M.I.T.), Cambridge, MA, USA. (INVITED LECTURE)
Falk M., Falková I., Ježková L., Davídková M., Bačíková A., Zadneprianetc M., Pagáčová E., Štefančíková L., Vachelová J., Michaelidesová A., Lukášová E., Boreyko A., Krasavin E.A., Kozubek S. DSB Repair and Primary and Secondary (DSB repair-induced) IRIF Clusters upon the Action of High-LET and Low-LET Radiations. 13th International Workshop on Radiation Damage to DNA, June 14-18, 2014, Massachusetts Institute of Technology (M.I.T.), Cambridge, MA, USA.
Pagáčová E., Falk M., Falková I., Štěpka K., Lukášová E., Michalová K., Zemanová Z., Matula P., Kozubek S. Chromosomal rearrangements of the chromosome 5 in myelodysplastic syndrome. Advanced Workshop on Interdisciplinary Views on Chromosome Structure and Function. 15 – 19 September 2014, Trieste, Italy
Ježková L., Boreyko A., Bulanova T., Falk M., Falkova I., Davidkova M., Kozubek S., Krasavin E., Kruglyakova E., Valentova E., Zadneprianetc M. Induction and repair of clustered DNA double strand breaks in human fibroblasts after irradiation with Boron ions and g-rays. 60th Annual International Meeting of Radiation Research Society. September 21-24, 2014, Las Vegas, Nevada, USA.
Falk M., Ježková L., Falková I., Lukášová E., Bačíková A., Davídková M., Zadneprianetc M., Pagáčová E., Vachelová J., Michaelidesová M., Boreyko A., Krasavin E., Kozubek S. CHARACTERISTICS OF IONIZING RADIATION, CHROMATIN STRUCTURE, AND DNA DOUBLE STRAND BREAK (MIS)REPAIR. 3rd International Conference “Radiation damage in Biomolecular Systems: Nanoscale insights into Ion Beam Cancer Therapy”, Nano-IBCT 2014 Conference, 27th – 31th October 2014, Boppard am Rhein, Germany. (INVITED LECTURE)
Falková I., Ježková L., Lukášová E., Bačíková A., Davídková M., Zadneprianetc M., Pagáčová E., Vachelová J., Michaelidesová A., Boreyko A., Krasavin E., Kozubek S., and Falk M. PRIMARY AND SECONDARY gH2AX FOCI CLUSTERS UPON IRRADIATING CELLS WITH DIFFERENT RADIATIONS AND THEIR ROLES IN FORMATION OF CHROMOSOMAL TRANSLOCATIONS. 3rd International Conference “Radiation damage in Biomolecular Systems: Nanoscale insights into Ion Beam Cancer Therapy”, Nano-IBCT 2014 Conference, 27th – 31th October 2014, Boppard am Rhein, Germany.
2013
Lacombe S., Porcel E., Le Sech C., Tillement O., Mowat P., Usami N., Kobayashi K., Stefancikova L., Falk M., Kozubek S., Schlatholter T. Hadrontherapy: nanoparticles in action. Radiation Damage in Biomolecular Systems: Nanoscale Insights into Ion-Beam Cancer Therapy, 2nd NANO-IBCT Conference 2013, 20-24 May 2013, Gdansk University of Technology, Sopot, Poland. (INVITED LECTURE)
Falk M., Falková I., Davídková M., L. Ježková L., Bačíková A., Štefančíková L., Vachelová J., Michaelidesová A., Kozubek S. Influences of radiation quality and higher-order chromatin structure on DSB induction and repair – comparison of gamma and proton irradiation. Radiation Damage in Biomolecular Systems: Nanoscale Insights into Ion-Beam Cancer Therapy, 2nd NANO-IBCT Conference 2013, 20-24 May 2013, Gdansk University of Technology, Sopot, Poland. (INVITED LECTURE)
Falk M. et al. Heterochromatin – Dr Jekyll and Mr Hyde of the DNA Damage Repair. 3rd World Congress on Molecular Biology, June 14-16, 2013, Suzhou, China. (INVITED LECTURE)
Falk M. From genomics to spatio-temporal organization of cellular processes: What can confocal microscopy tell us about the mechanism of DNA repair and formation of chromosomal translocations? Genomics 2013, November 12-14, 2013, DoubleTree by Hilton Hotel Chicago-North Shore, Chicago, IL, USA. (INVITED LECTURE)
Štefančíková L., Porcel E., Eustache P., Li S., Salado-Leza D., Réfrégier M., Kozubek S., Falk M. and Lacombe S. Nanoparticle cellular localization, uptake and effect on DNA damage response upon irradiation. Nano-IBCT meeting, 8th November 2013, Belfast, Ireland. (INVITED LECTURE)
Falk M., Lukáš Z., Falková I., Janoušová E., Fajkusová L., Štefančíková L., Zaorálková J., Hrabálková R., Feit J. A multilevel pathogenesis of myotonic dystrophy – dynamic DNA expansions, RNA expansions, and protein interactions come into play. High-Resolution Microscopy in the Biology of the Cell Nucleus, November 18 – 22, 2013, Hustopeče, Czech Rep.
Štefančíková L., Porcel E., Eustache P., Li S., Salado-Leza D., Kozubek S., Lacombe S. and Falk M. Nanoparticles cellular localization, uptake and effect on DNA damage response upon irradiation. High-Resolution Microscopy in the Biology of the Cell Nucleus, November 18 – 22, 2013, Hustopeče, Czech Rep.
Falkova I., Stefancikova L., Baranova E., Lukasova E., Jezkova L., Bacikova A., Kozubek S., Davidkova M., and Falk M. Heterochromatin structure prevents DSB repair but not formation of repair foci and protrusion of DSBs into the low-dense chromatin. Heavy Ion in Therapy and Space Radiation Symposium 2013 (HITSRS2013). May 15-18, 2013. Chiba, Japan.
Falk M., Falkova I., Davidkova M., Bacikova A., Stefancikova L., Lukasova E., Jezkova L., Vachelova J., Michaelidesova A., Kozubek S. „Secondary“ clustering of DSB repair foci and repair kinetics compared for g-rays and protons of different energies. Heavy Ion in Therapy and Space Radiation Symposium 2013 (HITSRS2013). May 15-18, 2013. Chiba, Japan.
Michaelidesová A., Vachelová J., Havránek V., Štursa J., Zach V., Falk M., Falková I., Ježková L., Vondráček V., Davídková M. Response of human normal fibroblasts to proton irradiation. 11th Microbeam Workshop, Microbeam Probes of Cellular Radiation Response. October 3rd & 4th, 2013. Bordeaux, France.
Michaelidesova A., Vachelova J., Falk M., Falkova I., Litvinchuk A., Havránek V., Štursa J., Zach V., Vondráček V., Davídková M. Response of normal skin fibroblasts to proton irradiation. 16th International Symposium on Microdosimetry. October 20 – 25.2013. Treviso, Italy.
Štefančíková L., Porcel E., Eustache P., Kozubek S., Falk M. and Lacombe S. Localization and radiosensitizing effect of Gd nanoparticles in cancer cells. SPRING 13 U: Design of multifunctional nano-objects for biomedical applications. May 27 – 31, 2013. Strasbourg, France.
Michaelidesová A., Vachelová J., Litvinchuk A., Falk M., Falková I., Havránek V., Štursa J., Vondráček V., Davídková M. Response of cell cultures of normal human skin fibroblasts to proton irradiation. XXXV. Dny radiační ochrany, November 11 – 15, 2013. Třeboň, Czech Republic.
2012
Falk M., Falková I., Ježková L., Davídková M., Bačíková A., Lukášová E., Štefančíková L., Vachelová J., Michaelidisová A., Kozubek S. gH2AX/53BP1 foci formation and DSB repair in cells irradiated with g-rays and protons of different energy – influence of higher-order chromatin structure. Quantum Scattering Codes and Monte Carlo Simulations to Model Dynamical Processes in Biosystems, Nano-IBCT Workshop, 7. – 9. November 2012, Madrid, Spain. (INVITED LECTURE)
Falková I., Ježková L., Baranová E., Štefančíková L., Lukášová E., Kozubek S., Boreyko A., Krasavin E., and Falk M. gH2AX/53BP1 foci formation and DSB repair in cycling cells and differentiated cells irradiated with g-rays. Quantum Scattering Codes and Monte Carlo Simulations to Model Dynamical Processes in Biosystems, Nano-IBCT Workshop, 7. – 9. November 2012, Madrid, Spain. (INVITED LECTURE)
Falk M. et al. Repair of DNA double strand breaks in the context of chromatin and nuclear structure. 15th. November, 2012, Palacky Univerzity, Olomouc, Czech Republic. (INVITED LECTURE)
Falk M., Štefančíková L., Lukášová E., Bačíková A., Falková I., Kozubek S. Funkce, poškození a reparace chromatinu – představení činnosti skupiny; vliv uspořádání chromatinu v jádře na vznik jednoduchých a komplexních přestaveb chromosomů. Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Condition. Project Excellence 302/12/G157 Workshop No. 1. 29 – 30 March 2012, Brno, Czech Republic
Lukášová E., Bačíková A., Štefančíková L., Falk M., Kozubek S., Trbušek M., Šebejová L. Zvýšená fosforylace H2AX, změny chromatinové struktury a buněčná smrt po zablokování replikace a Chk1 kinázy v leukemických buňkách. Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Condition. Project Excellence 302/12/G157 Workshop No. 1. 29 – 30 March 2012, Brno, Czech Republic
Štefančíková L., Falk M., Lukášová E., Bačíková A., Kozubek S. Senzitizace nádorových buněk k záření pomocí nanočástic. Dynamics and Organization of Chromosomes in the Cell Cycle and during Differentiation under Normal and Pathological Condition. Project Excellence 302/12/G157 Workshop No. 1. 29 – 30 March 2012, Brno, Czech Republic
Ševčík J, Lhota F, Kleiblová P, Hojný J, Falk M, Štefančíková L, Měšťák O, Pavlišta D, Pohlreich P, Kleibl Z. Alternative splicing of BRCA1 – desired tool for DNA repair regulation or “messy garbage” of splicing events? Genes, Genetics & Genomics 2012 (G3 2012), May 10th-11th, 2012, the First Faculty of Medicine, Charles University, Prague, Czech Republic
Falk M., Lukášová E., Štefančíková L., Bačíková A., and Kozubek S. Nuclear architecture and DSB repair. International Workshop on Radiation Damage to DNA, June 2nd – 6th, 2012, Prague, Czech Republic
Baranova E., Štefančíková L., Falková I., Kozubek S., Boreyko A., Krasavin E., and Falk M. Comparison of DNA γH2AX/53BP1 foci formation, nuclear distribution and DNA double strand break repair compared for skin fibroblasts and lymphocytes either irradiated with gamma-rays or incubated with hydrogen peroxide. International Workshop on Radiation Damage to DNA, June 2nd – 6th, 2012, Prague, Czech Republic
Lukášová E., Falk M., Štefančíková L., Bačíková A., and Kozubek S. Chromatin changes during DSB repair in euchromatin and heterochromatin. International Workshop on Radiation Damage to DNA, June 2nd – 6th, 2012, Prague, Czech Republic
Falk M., Lukášová E., Štefančíková L., Falková I., Ježková L., Bačíková A., Davídková M., Vachelová J., Michaelidisová A., Kozubek S. DNA damage and repair in the context of chromatin structure. Advanced Confocal Microscopy and Living Cell Studies, 15 – 19 October, 2012, Brno, Czech Republic
Štefančíková L., Porcel E., Lacombe S., Falk M., Kozubek S. Localization of nanoparticles in cancer cells. Advanced Confocal Microscopy and Living Cell Studies, 15 – 19 October, 2012, Brno, Czech Republic
Vachelová J., Michaelidesová A., Pachnerová Brabcová K., Falk M., Falková I., Ježková L., Davídková M. Pilotní studie radiačního poškození fibroblastů“ XXXIV. Dny radiační ochrany, 5. – 9. 11. 2012, Třeboň, CR
Falk M., Štefančíková L., Lukášová E., Bačíková A., Falková I., Kozubek S. Reparace DNA a vliv uspořádání chromatinu v jádře na vznik jednoduchých a komplexních přestaveb chromosomů. Advanced Confocal Microscopy and Living Cell Studies, enclosed Meeting of GACR Project, Center of Excellence No.: P302/12/G157, 15 – 19 October, 2012, Brno, Czech Republic
Lukášová E., Bačíková A., Štefančíková L., Falk M., Kozubek S., Trbušek M., Šebejová L. Zvýšená fosforylace H2AX, změny chromatinové struktury a buněčná smrt po zablokování replikace a Chk1 kinázy v leukemických buňkách – pokroky ve výzkumu. Advanced Confocal Microscopy and Living Cell Studies, enclosed Meeting of GACR Project, Center of Excellence No.: P302/12/G157, 15 – 19 October, 2012, Brno, Czech Republic
Štefančíková L., Falk M., Lukášová E., Bačíková A., Kozubek S. Senzitizace nádorových buněk k záření pomocí nanočástic – pokroky ve výzkumu. dvanced Confocal Microscopy and Living Cell Studies, enclosed Meeting of GACR Project, Center of Excellence No.: P302/12/G157, 15 – 19 October, 2012, Brno, Czech Republic
2011
Falk M., Lukášová E., Kozubek S., Štefančíková L. Higher-order chromatin structure in DNA double-strand break induction, repair and formation of chromosomal translocations. Brunel University (Invited by Dr. Rhona Anderson), June 29 – July 1, 2011, London, Great Britain. (INVITED LECTURE)
Falk M., Lukášová E., Kozubek S., Štefančíková L. Higher-order chromatin structure in DNA double-strand break induction, repair and formation of chromosomal translocations. The ARR & UKEMS Joint Annual Meeting, June 29 – July 1, 2011, Nottingham University, Jubilee Campus, Nottingham, Great Britain. (INVITED LECTURE)
Falk M., Lukášová E., Kozubek S., Štefančíková L. Function of chromatin structure and dynamics in DNA damage, repair and misrepair. Sixth International Summer Student School on Nuclear Physics Methods and Accelerators in Biology and Medicine, 2 – 12 th July 2011, Dubna, Russia. (INVITED LECTURE)
Falk M., Vojtíšková M., Lukáš Z., Falková I., Štefančíková L., Kozubek S. Current detection possibilities of unstable alleles in the myotonic dystrophy and Huntington’s disease loci. EPS Montreal Occupational Safety and Health Forum, 15th – 16th August 2011, Montreal, Canada. (INVITED LECTURE)
Falk M., Lukášová E., Kozubek S., Štefančíková L., Weiterová L. Induction, repair and misrepair of DNA double-strand breaks (DSBs) in the context of higher-order chromatin structure. The 14th International Congress of Radiation Research, 28.08 – 01.09.2011, Warsaw, Poland. (INVITED LECTURE)
Falk M., Lukasova E., Kozubek S., Stefancikova L., Weiterova L. Spatio-Temporal Aspects of DNA Double-Strand Break Repair and Formation of Chromosomal Translocations. The 1st Nano-IBCT Conference (in the framework of the COST Action MP1002 (Nano-scale Insights into Ion Beam Cancer Therapy), October 2nd to October 6th, 2011, Caen, France. (INVITED LECTURE)
Falk M, Lukášová E, Kozubek S, Štefančíková L. Spatio-temporal questions of DNA double-strand break repair and formation of chromosomal translocations. International Symposium for Radiation Research and Medical Physics. May 30 – June 2, 2011. Shanghai, China.
2010
Falk M., Lukasova E., Kozubek S., Bacikova A.: Induction and repair of DNA double-strand breaks in the context of higher-order chromatin structure. 7th International Conference on Radiation Damage in Biomolecular Systems (RADAM 2010), 30 June – 4 July 2010, Madrid, Spain. (INVITED LECTURE)
Falk M., Lukasova E., Bacikova A., Kozubek S. DSB damage in structurally and functionally distinct higher-order chromatin domains – relationship between nuclear architecture, DSB induction and repair. ABCAM conference on Maintenance of Genome Stability 2010, Antigua, March 8-11, 2010.
Falk M., Lukáš Z., Falková I., Hrabalkova R., Zaoralkova J. Ribonuclear foci in differentiated tissues of patients with DM2. 15th International Congress of the World Muscle Society, Kumamoto, Japan, October 12-16, 2010.
Sevcik J., Falk M., Kleiblova P., Lhota F., Pohlreich P., Kleibl Z. In vitro analysis of population specific BRCA1 splicing variants. 21st Meeting of the European Association for Cancer Research, Oslo, Norway, 26 – 29 June 2010.
2009
Falk M., Lukasova E., Kozubek S.: The role of higher-order chromatin structure and nuclear topography in DSB induction, repair and chromatin translocation. ESF-EMBO Symposium: Spatio-Temporal Radiation Biology: Transdisciplinary Advances for Biomedical Applications, 16-21 May 2009, Hotel Eden Roc, Sant Feliu de Guixols (Costa Brava), Spain. (INVITED LECTURE)
Falk M., Lukasova E., Bacikova A., Kozubek S.: The role of chromatin structure in DNA damage and its monitoring. ERRS09 – Prague, 37th Annual Meeting of the European Radiation Research Society, 26-29th August 2009, Prague, Czech Republic. (INVITED LECTURE)
2008
Falk M., Lukášová E., Kozubek S. Different sensitivity and response of functionally distinct chromatin domains to DSB induction. 10th Biennial Meeting of the DGDR (German Society for Research on DNA Repair, Berlin, Germany, 2-5 September 2008
Falk M., Lukášová E., Kozubek S. Direct visualization of DSB induction and repair in gene dense (RIDGE) and gene poor (anti-RIDGE) chromatin domains. Biochemical Society Annual Symposium – DNA Damage: From Causes to Cures, Cambridge, United Kingdom, December 15-17, 2008.
2007
Pelicci P.G. (results of Falk M., Lukášová E. and Kozubek S. included): PML-RAR − A Model to Cure Leukemia. Salk Institute, Nature and Foundation IPSEN Conference on Biological Complexity: Diseases of Transcription. January 11-14, 2007, Salk Institute, La Jolla, CA, USA. (INVITED LECTURE)
Falk M., Lukášová E., Gabrielová B., Ondřej V., Kozubek S. Local changes of higher-order chromatin structure during DSB-repair. RADAM Conference 2007 – Radiation Damage in Biomolecules Conference, Dublin, Ireland, June 19-22, 2007.
Falk M., Lukášová E., Gabrielová B, Kroupová I. and Kozubek S. Nuclear Organization and Dynamics of the DSB-repair − Direct Visualization of Double Strand Breaks in Functionally Different Chromatin Domains. Salk Institute, Nature and Fondation IPSEN Conference on Biological Complexity: Diseases of Transcription, Salk Institute, La Jolla, CA, USA, January 11-14, 2007. Falk M., Lukášová E., Gabrielová B., Ondřej V., Kozubek S, Kroupova I. DSB-repair requires specific sequence of higher-order chromatin structure changes – Direct visualization of double strand breaks in functionally different chromatin domains. Symposium on Radiation Effects of Biomedical Interest, Madrid, Spain, February, 22-25, 2007.
Mezinárodní konference Radiobiologija
29. – 30. září 2016
Institut radiobiologie Akademie věd Republiky Bělarus, Gomel
http://www.irb.basnet.by/ru/meropriyatiya/mezhdunarodnaya-nauchnaya-konferenciya-radiobiologiya-minimizaciya-radiacionnyx-riskov/
Mezinárodní konference Conference on Cell Biology and Radiobiology. Satellite Symposium of the 6th International Conference on Genomics & Pharmacogenomics (held in Berlin, 2016)
9. – 10. září 2016
Biofyzikální ústav Akademie věd České republiky, Královopolská 135, Brno
About the Conference: The conference is focused on: •Superresolution light microscopy (nanoscopy) in cell biology and radiobiology •DNA damage and repair •Biological effects of different quality radiations •Complex cellular response to irradiation •Tumor cell radiosensitization and normal cell radioprotection •Mutagenesis; genetic and other defects influencing (tumor) cell radiosensitivity/radioresistance •Biological dosimetry and crisis planning •Classic radiotherapy versus proton and ion-beam cancer therapy •Mechanisms of chromatin aberrations formation •Leukemia and cancer development/pathogenesis •Higher-order chromatin structure and function •Organization of the cell nucleus
Contacts: falk@ibp.cz; ivafalk@seznam.cz; +420-541517116 (office), +420-606207584 (mobile Iva Falková) +420-728-084060 (mobile, Martin Falk)
Mezinárodní konference 6th International Conference on Genomics & Pharmacogenomics
12. – 14. září 2016
Sheraton Berlin Grand Hotel Esplanade, Lützowufer 15, 10785 Berlin, Germany (Co-organized by Martin Falk)
Mezinárodní konference XVII. Štiavnické dni
4. – 6. října 2016
Chata HRON, Počúvadlo jazero 140, 969 01 Banská Štiavnica
Mírové využívání atomové energie; využívání ionizujícího záření ve vědě a v praxi; monitorování ionizujícího záření v životním prostředí; ochrana lidí před ionizujícím zářením; regulace radonu v budovách podle Směrnice 2013/59/Euratom a nakládání s odpady.
Kontakt: RNDr. Petr Škrabálek, Ph.D., Združenie pre reguláciu rizika z radónu, Banská Štiavnica, tel.: +421 456 929 080, mail zrrr.akademicka@gmail.com
Mezinárodní konference WORLD CBRN & MEDICAL CONGRESS
19. – 21. října 2016
Praha
www.future-forces-forum.org
Mezinárodní konference Laser Florence 2017
The International Academy of Laser Medicine and Surgery World Congress will take place in Florence
9. – 11. listopad 2017
http://www.laserflorence.eu/